Q.Light Photodynamic Therapy (PDT)
Q.Light PDT is applied in Dermatology for the following pre-cancerous indications:
Morbus Bowen (Bowens disease)
Basal Cell Carcinoma
Initial spine cellular Carcinoma
The topical photodynamic therapy (PDT) is based on the selective destruction of epidermal and dermal skin tumour cells (depth penetration is 3–4 mm) through application of photosensitive drugs. Tumour cells accumulate photosensitive drugs for the reason of enhanced metabolism. Due to radiation of high energetic light in the visible red spectrum, reactive oxygen species (ROS) are produced which leads to death of the targeted tumour cells.
The development of the PDT Treatment filter module is based on successful research into photodynamic therapy and on clinical licensing from Metvix®. PDT lamp has been especially developed for dermatologists and complies with regulations for medical products as set out in the Guidelines for Medical Products 93/42 EWG; it has also a certification status based on the international standards and requirements for regulatory purposes of DIN EN ISO 13485:2003.
For the optimal therapeutic effect a source of red, incoherent light is generated (Szeimies et al. 1996; Fijan et al.1995). Q.Light PDT system emits red, incoherent light in the spectrum from 620nm to 780nm. In accordance with the above table treatment time is between 13 and 45 minutes with the average time of 25 min.